Cut Size Calculation of Cascade Impactor

ABSTRACT : Measurements : Particle Size Measurements for OINDP Quality – I : Cascade Impactor

Measurements: Particle Size Measurements for OINDP Quality – I: Cascade Impactor Dr. Jolyon P. Mitchell Ph.D., FRSC (UK), C.Chem., C.Sci. Aerosol aerodynamic particle size distribution (APSD) is a critical quality attribute for determining inhaler performance in the quality control environment. This is because likely deposition of inhaled medication in the various regions of the human respirato...

Deposition Dosages of Three Cromolyn Forms by Cascade Impactor

Among inhaled asthma therapies, the present study aimed to identify factors for selecting the type of inhalation therapy for asthma. Three methods are used to deliver inhaled cromoglycate, and the airway deposition rate was evaluated using a cascade impactor with 3 dosage forms: dry powder (DP), pressurized metered dose inhaler (pMDI), and solution (jet- and mesh-types). The percentage of parti...

Medical nebulizer performance: effects of cascade impactor temperature.

BACKGROUND During operation of a jet nebulizer, the temperature of the nebulizer outlet could decrease by more than 10 degrees C, depending on the nebulizer type and operating conditions, such as driving flow rate and fill volume. The droplet size distribution generated from the nebulizer can be measured by a cascade impactor. However, when the cascade impactor is operated at ambient room tempe...

Determining chondritic impactor size from the marine osmium isotope record.

Decreases in the seawater 187Os/188Os ratio caused by the impact of a chondritic meteorite are indicative of projectile size, if the soluble fraction of osmium carried by the impacting body is known. Resulting diameter estimates of the Late Eocene and Cretaceous/Paleogene projectiles are within 50% of independent estimates derived from iridium data, assuming total vaporization and dissolution o...

On the Calculation of Cascade Flows -